Levothyroxine Hypothyroidism and/or minimized Charge of hypothyroidism may possibly take place when orlistat and levothyroxine are taken simultaneously (see part 4.four). This may be due get more info to a lowered absorption of iodine salts and/or levothyroxine. Orlistat stops about a 3rd in the Unwanted fat that you simply eat from becoming diges